Cyntropic
Processes pharmaceutical adverse-event case reports into submission-ready safety documents, with expert human sign-off.
Company basics
- HQ
- United States
- Delivery model
- Hybrid (shared operation)
- Pricing model
- Not disclosed
Scope
- Industries
- Healthcare
- Regions
- unstated
- Languages
- unstated
About Cyntropic
Cyntropic is a San Francisco Bay Area company that automates pharmacovigilance case processing, from intake through submission to regulators such as the FDA and EMA. It is aimed at emerging biopharma, larger pharmaceutical companies and contract research organizations that handle individual case safety reports.
The site describes intake and triage from forms, PDFs, emails and literature, AI-driven processing such as MedDRA coding, causality assessment and narrative generation, and a review layer in which pharmacovigilance specialists sign off before submission. The company states human-in-the-loop is a core design element and that every submission-bound case has expert review and approval with a combined AI and human audit trail. Output formats include E2B(R3) XML, CSV and custom API endpoints. The company describes an API-first design that connects to existing safety databases and works as a layer without requiring database replacement, and it lists a pilot option.
The company states its founding team combines biopharmaceutical and AI expertise.
What they do
- End-to-end delivery (you don't operate the tools)Source · checked 2026-09-29Handles ICSR intake through submission-ready documents; safety team reviews rather than operates tools.
- Human review includedSource · checked 2026-09-29Human expert sign-off on every submission-bound document; states never AI-only output.
- Works inside your existing systemsSource · checked 2026-09-29API-first; connects to existing safety databases without replacing them.
- API or data exportSource · checked 2026-09-29API-first architecture and exportable AI+human audit trails.
Pricing
- Pricing model
- Not disclosed
- Published starting price
- Not published
- Pricing page
- Not published
Evidence of outcomes
BOutcomes reported by the company or its investors.Self-reported 91-96% extraction accuracy from a Phase 1 evaluation of 44 cases (whitepaper listed at cyntropic.com/resources.html); no named customers.
A: third-party verifiable outcomes · B: outcomes reported by the company or its investors · C: no publicly verifiable outcomes yet. Demos, forecasts and slogans do not count.
FAQ
Do we have to replace our safety database?
No. The company states its API-first design connects to existing safety databases and works as a layer alongside existing infrastructure. (Source: https://cyntropic.com)
Who approves cases before submission?
The company states every submission-bound case is reviewed and approved by expert pharmacovigilance staff, with a complete AI and human audit trail. (Source: https://cyntropic.com)
Is there a way to try the service first?
The site lists a pilot option, and states customized systems are implemented within weeks. (Source: https://cyntropic.com)
Our read
Editorial view based on public information — not an endorsement.
Capabilities
| Check | Status | Source |
|---|---|---|
| End-to-end delivery (you don't operate the tools) | Confirmed | Source · checked 2026-09-29Handles ICSR intake through submission-ready documents; safety team reviews rather than operates tools. |
| Human review included | Confirmed | Source · checked 2026-09-29Human expert sign-off on every submission-bound document; states never AI-only output. |
| Signed off by licensed professionals (CPA, attorney…) | Not stated | — |
| Works inside your existing systems | Confirmed | Source · checked 2026-09-29API-first; connects to existing safety databases without replacing them. |
| Private / on-prem deployment available | Not stated | — |
| API or data export | Confirmed | Source · checked 2026-09-29API-first architecture and exportable AI+human audit trails. |
| Multilingual delivery | Not stated | — |
Commitments
| Check | Status | Source |
|---|---|---|
| Public delivery SLA | Not stated | — |
| Outcome-based pricing | Not stated | — |
| Refund / satisfaction guarantee | Not stated | — |
| Customer data not used for training | Not stated | — |
| SOC 2 | Not stated | — |
| ISO 27001 | Not stated | — |
| HIPAA | Not stated | — |
| GDPR | Not stated | — |
| Named party responsible for outcomes | Not stated | — |
Funding
Not disclosed
How we check
Every check below links to its source and shows when we checked it. "Not stated" means we found no public statement — it does not mean "no".
Other routes
Use a tool yourself
Get it implemented
Sources
- Company website: https://cyntropic.com/
Change history
- 2026-09-29 · Listed on Toolsfine